Tetrahedron

Sulfonyl derivatives of benzotriazole: Part 1. A novel approach to the activation of carboxylic acids

AR Katritzky, N Shobana, J Pernak, AS Afridi, WQ Fan

Index: Katritzky, Alan R.; Shobana; Pernak, Juliusz; Afridi; Fan, Wei-Qiang Tetrahedron, 1992 , vol. 48, # 37 p. 7817 - 7822

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Citation Number: 74

Abstract

1-Acylbenzotriazoles (8, R= Me, Et, n-Bu and Ph) are prepared in good yields by fusion of benzotriazole and acid chlorides at 80–100° C. In cases when the corresponding acid chlorides are not available, 1-acylbenzotriazoles are conveniently available from 1-(1- methanesulfonyl) benzotriazole and the respective carboxylic acids as illustrated by the preparation of 2-, 3-, and 4-pyridoyl-, 2-pyrrolylcarbonyl-and 2-furoyl-benzotriazole in ...