Evidence for intermediates and a change in rate-limiting step in the aminolysis of the carcinogen N-methyl-N'-nitro-N-nitrosoguanidine by cyclic amines

DN Wichems, S Nag, J Mills…

Index: Journal of the American Chemical Society, , vol. 114, # 23 p. 8846 - 8851

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Citation Number: 6

Abstract

... 0002-7863/92/ 15 14-8846$03.00/0 0 1992 American Chemical Society Page 2. ... SOC., Vol. ... the N-nitroso-N-alkyl f~nctionality.~ MNNG is also routinely used in the study of alkylating patterns of DNA.5 An understanding of the detailed aqueous decomposition chemistry of MNNG ...