Synthesis and immunomodulating activity of 1-amino-2-thiohydantoin derivatives

M Blanc, M Cussac, A Boucherle, G Leclerc

Index: Blanc; Cussac; Boucherle; Leclerc European Journal of Medicinal Chemistry, 1992 , vol. 27, # 8 p. 839 - 843

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Citation Number: 15

Abstract

Abstract 1-Amino-2-thiohydantoin derivatives have been synthesized. Immunomodulating and anticancer activities have been studied. Their activity on the immune system is complex, being either immunodepressive or immunostimulatory according to the doses, or mainly immunostimulatory. These compounds were devoid of any anticancer activity.