Studies in the Indole Series. XVI. 1 Oxindole-3-alanine and Dioxindole-3-alanine

PL Julian, EE Dailey, HC Printy, HL Cohen…

Index: Julian et al. Journal of the American Chemical Society, 1956 , vol. 78, p. 3503,3506

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Citation Number: 17

Abstract

A new synthesis of oxindole-3-alanine is devised and three distinct improvements and safeguards are suggested for the Cornforth synthesis of this substance, thus making this amino acid a readily available material for further syntheses of substances related to natural products. Dioxindole-3-alanine, suggested as a possible intermediate in the metabolic transformation of tryptophan into formylkynurenine, also has been synthesized. ...