Tetrahedron

EDTA and DTPA modified ligands as sequestering agents for uranyl decorporation

…, G Arrachart, R Turgis, D Lecerclé, A Favre-Reguillon…

Index: Leydier, Antoine; Lin, Yi; Arrachart, Guilhem; Turgis, Raphael; Lecercle, Delphine; Favre-Reguillon, Alain; Taran, Frederic; Lemaire, Marc; Pellet-Rostaing, Stephane Tetrahedron, 2012 , vol. 68, # 4 p. 1163 - 1170

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Citation Number: 10

Abstract

Synthesis of modified EDTA and DTPA ligands and determination of their binding affinities for the uranyl cation are described. Thanks to a screening method, based on a chromophoric complex displacement procedure, chelating properties were studied in aqueous media under various pH conditions for evaluation of their in vivo uranyl-removal efficacy. Each ligand showed a more or less pronounced affinity for uranium. Specific ligands based on ...

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