Carbon-carbon bond formation by the reaction of organolithiums with α-lithiated cyclic enol ethers. Stereoselective synthesis of β-and γ-hydroxy di-and tri-substituted …
T Nguyen, E Negishi
Index: Nguyen, Thinh; Negishi, Ei-ichi Tetrahedron Letters, 1991 , vol. 32, # 42 p. 5903 - 5906
Full Text: HTML
Citation Number: 27
Abstract
Abstract α-Lithiation of dihydrofuran, benzofuran, and dihydropyran followed by treatment with various organolithiums stereoselectively produces in good yields the corresponding ring-opened (E)-alkenyllithiums, ie,(E)-β (or γ)-hydroxy-ω-alkenyl-ω-lithioalkenes, the lithium atom of which can be readily replaced with H, D, or C groups, such as CO 2 and Me.
Related Articles:
[Fargeas, Valerie; Le Menez, Patrick; Berque, Isabelle; Ardisson, Janick; Pancrazi, Ange Tetrahedron, 1996 , vol. 52, # 19 p. 6613 - 6634]
1, 2-metallate rearrangements: stannyl and (stannyl) vinyl transfers
[Menez, Patrick Le; Fargeas, Valerie; Poisson, Jacques; Ardisson, Janick; Lallemand, Jean-Yves; Pancrazi, Ange Tetrahedron Letters, 1994 , vol. 35, # 42 p. 7767 - 7770]