Unsaturated and carbocyclic nucleoside analogs: synthesis, antitumor and antiviral activity

S Phadtare, D Kessel, TH Corbett…

Index: Phadtare, Shashikant; Kessel, David; Corbett, Thomas H.; Renis, Harold D.; Court, Barbara A.; Zemlicka, Jiri Journal of Medicinal Chemistry, 1991 , vol. 34, # 1 p. 421 - 429

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Citation Number: 61

Abstract

(17) Phadtare, s.; Zemlicka, J. Nucleic Acids Res., Symp. Ser. 1987, No. 18, 25. a. K2CO3, DMSO. b. NBu4 F, THF. c. 0.1 M HCI, reflux. d. 0.1 M NaOH, reflux. hibitors of human immunodeficiency(HIV), the etiologic agent of acquired immunodeficiency syndrome (AIDS). By contrast, butynols 6g-j, which were also a subject of recent reports? 16J8v20 did not exhibit significant biological activity in any system examined to date. Lastly, a new group ...