Total syntheses of marchantin A and riccardin B, cytotoxic bis (bibenzyls) from liverworts

…, H Sumitomo, K Matsumura, M Tsukamoto…

Index: Kodama; Shiobara; Sumitomo; Matsumura; Tsukamoto; Harada Journal of Organic Chemistry, 1988 , vol. 53, # 1 p. 72 - 77

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Citation Number: 40

Abstract

Results Synthesis of Marchantin A (1). According to the scheme described above, we started the synthesis from the preparation of the AC-ring segment. The acetonide 14 of methyl gallate was coupled with p-bromobenzaldehyde in the presence of anhydrous potassium carbonate and cupric oxide (Scheme 11). After the mixture was refluxed in pyridine for 12 h, the diphenyl ether 15 was obtained in 68% yield. The D-ring segment 16 was readily ...