Pyrrolopyrazines as selective spleen tyrosine kinase inhibitors

F Padilla, N Bhagirath, S Chen, E Chiao…

Index: Journal of Medicinal Chemistry, , vol. 56, # 4 p. 1677 - 1692

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Citation Number: 18

Abstract

... Journal of Medicinal Chemistry. ... Syk's potential as a therapeutic target for an array of inflammatory diseases has led to many pharmaceutical companies, as well as academic institutions, becoming involved in the development of inhibitors of Syk. ...