Journal of medicinal chemistry

Studies on Methylglyoxal Bis (guanylhydrazone) 1 Analogs. III. Trifluoromethylglyoxal Bis (guanylhydrazone) 2 and 1, 2-Bis (guanidinoamino) propane3, 4

EG Podrebarac, CC Cheng

Index: Podrebarac,E.G.; Cheng,C.C. J. Med. Chem., 1964 , vol. 7, p. 806 - 808

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Citation Number: 9

Abstract

I11 IV v salt. The sulfate of I1 was similarly prepared from I11 and aminoguanidine sulfate. Both products were difficult to purify. The ultraviolet absorption maxima for the two were identical (A::: 304 mp), yet quite different from the characteristic absorption for I and its homologs (A&:: 283 mp). 5 In view of the analytical difficulties and the" abnormal" ultraviolet absorption, an attempt was made to determine whether the products in the foregoing ...