New furano-and pyrrolo [2, 3-d] pyrimidine nucleosides and their 5′-O-triphosphates: Synthesis and biological properties

…, IA Krasnitskaya, OA Smirnova, IL Karpenko…

Index: Ivanov; Krasnitskaya; Smirnova; Karpenko; Belanov; Prasolov; Tunitskaya; Alexandrova Russian Journal of Bioorganic Chemistry, 2008 , vol. 34, # 5 p. 593 - 601

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Citation Number: 13

Abstract

Abstract Bicyclic furano [2, 3-d] pyrimidine ribonucleosides were synthesized by Pd (0)-and CuI-catalyzed coupling of 5-iodouridine with terminal alkynes. The treatment of the resulting nucleosides with ammonia or methylamine solution in aqueous alcohol resulted in pyrrolo ...