Regio-and stereoselective synthesis of 1, 4-dihydropyridines by way of an intramolecular interaction of a thiocarbonyl or carbonyl with a pyridinium nucleus
S Yamada, T Misono, M Ichikawa, C Morita
Index: Yamada, Shinji; Misono, Tomoko; Ichikawa, Mayumi; Morita, Chisako Tetrahedron, 2001 , vol. 57, # 43 p. 8939 - 8949
Full Text: HTML
Citation Number: 44
Abstract
Chiral 1, 4-dihydropyridines were prepared by the regio-and stereoselective addition of ketene silyl acetals and organometallic reagents to pyridinium salts. In the addition reaction, an intramolecular interaction between the thiocarbonyl or carbonyl with the pyridinium nucleus plays an important role in bringing about the selectivities. The absolute configuration of the newly produced stereogenic center of the 1, 4-dihydropyridines was ...
Related Articles:
New dsDNA binding unnatural oligopeptides with pyrimidine selectivity
[Zhang, Zhenyu; Chaltin, Patrick; Van Aerschot, Arthur; Lacey, Jeff; Rozenski, Jef; Busson, Roger; Herdewijn, Piet Bioorganic and Medicinal Chemistry, 2002 , vol. 10, # 11 p. 3401 - 3413]