Ketyl-allene cyclizations promoted by samarium (II) iodide
GA Molander, EP Cormier
Index: Molander, Gary A.; Cormier, Elizabeth Pollina Journal of Organic Chemistry, 2005 , vol. 70, # 7 p. 2622 - 2626
Full Text: HTML
Citation Number: 51
Abstract
Samarium (II) iodide has proven to be an effective reagent for intramolecular reductive coupling reactions. Previous investigations of intramolecular ketyl-olefin coupling reactions provided carbocycles in excellent yield and good diastereoselectivity. This method has been extended to ketyl cyclizations with allenes. Substrates leading to both carbocycles and heterocycles in a selective manner are explored.
Related Articles:
[Zhang, Zhibin; Liu, Cong; Kinder, Robert E.; Han, Xiaoqing; Qian, Hua; Widenhoefer, Ross A. Journal of the American Chemical Society, 2006 , vol. 128, # 28 p. 9066 - 9073]
CuI??Catalyzed Synthesis of Functionalized Terminal Allenes from 1??Alkynes
[Luo, Hongwen; Ma, Shengming European Journal of Organic Chemistry, 2013 , # 15 p. 3041 - 3048]
[Audin, Patrick; Doutheau, Alain; Gore, Jacques Bulletin de la Societe Chimique de France, 1984 , vol. 2, # 7-8 p. 297 - 306]
[Zhang, Zhibin; Liu, Cong; Kinder, Robert E.; Han, Xiaoqing; Qian, Hua; Widenhoefer, Ross A. Journal of the American Chemical Society, 2006 , vol. 128, # 28 p. 9066 - 9073]
Acylation-cyclization of allenes
[Bates, Roderick W.; Rama-Devi, Thota; Ko, Huei-Huei Tetrahedron, 1995 , vol. 51, # 47 p. 12939 - 12954]