Discovery of N-[(1 S, 2 S)-3-(4-Chlorophenyl)-2-(3-cyanophenyl)-1-methylpropyl]-2-methyl-2-{[5-(trifluoromethyl) pyridin-2-yl] oxy} propanamide (MK-0364), a novel, …

LS Lin, TJ Lanza, JP Jewell, P Liu…

Index: Journal of Medicinal Chemistry, , vol. 49, # 26 p. 7584 - 7587

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Citation Number: 116

Abstract

... Journal of Medicinal Chemistry. ... These efforts led to the identification of compound 48 for development as a clinical candidate for the treatment of obesity. Obesity is a serious and chronic medical condition that is rapidly growing throughout the world. ...