Inhibitors of dipeptidyl peptidase IV-recent advances and structural views

D Hunziker, M Hennig, JU Peters

Index: Eisai Co., Ltd. Patent: EP1338595 A2, 2003 ;

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Citation Number: 58

Abstract

... given to the analysis of several X-ray structures of enzyme-inhibitor co-crystals. ... Boehringer Ingelheim, Novo Nordisk and Eisai filed patent applications for a variety of highly ... Two years later, an application from the same company claiming aminomethylquinolines around 38 (134 ...