A Simple One-Pot Synthesis of 2-Aryl-5-alkyl-Substituted Oxazoles by Cs2CO3-Mediated Reactions of Aromatic Primary Amides with 2, 3-Dibromopropene
N Yasmin, JK Ray
Index: Yasmin, Nasima; Ray, Jayanta K. Synlett, 2009 , # 17 p. 2825 - 2827
Full Text: HTML
Citation Number: 3
Abstract
Abstract A simple and efficient method for the synthesis of 2-aryl-5-alkyl-substituted oxazoles has been developed. A series of 2, 5-disubstituted oxazoles were synthesized in a single step by Cs 2 CO 3-mediated reactions of aromatic primary amides with 2, 3-
Related Articles:
A practical method for oxazole synthesis by cycloisomerization of propargyl amides
[Wipf, Peter; Aoyama, Yasunori; Benedum, Tyler E. Organic Letters, 2004 , vol. 6, # 20 p. 3593 - 3595]
[Andrade, Gabriel A.; Pistner, Allen J.; Yap, Glenn P. A.; Lutterman, Daniel A.; Rosenthal, Joel ACS Catalysis, 2013 , vol. 3, # 8 p. 1685 - 1692]
Amide bond formation using an air-stable source of AlMe 3
[Novak, Andrew; Humphreys, Luke D.; Walker, Matthew D.; Woodward, Simon Tetrahedron Letters, 2006 , vol. 47, # 32 p. 5767 - 5769]
[Andrade, Gabriel A.; Pistner, Allen J.; Yap, Glenn P. A.; Lutterman, Daniel A.; Rosenthal, Joel ACS Catalysis, 2013 , vol. 3, # 8 p. 1685 - 1692]