Journal of the Chinese Chemical Society

Synthesis of Newly Substituted Pyrazoles and Substituted Pyrazolo [3, 4??b] Pyridines Based on 5??Amino??3??Methyl??1??Phenylpyrazole

TI El??Emary

Index: El-Emary, Talaat I. Journal of the Chinese Chemical Society, 2007 , vol. 54, # 2 p. 507 - 518

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Citation Number: 19

Abstract

Abstract The reaction of the aminopyrazole 1 with benzenesulfonyl chloride, arenediazonium salt, chloroacetyl chloride, ethoxy methyleneamlononitrile and with ethyl 2- cyano-3-ethoxyacrylate gave the substituted 3-methyl-1-phenylpyrazole 2–5a, b. Compound 5b was cyclized to 6 and to 7 by treating it with AlCl 3 and with POCl 3, respectively. Compound 6 converted to 7 by boiling it in POCl 3/PCl 5. Compound 10b was produced ...