Synthesis, antibacterial, and analgesic activity of novel 4-hydroxy-3-(phenylthio)-2 h-chromen-2-ones and 4-hydroxy-3-[imidazol/tetrazolo-2-yl) thio]-2 h-chromen-2- …

…, ND Satyanarayan, HS Bhojya Naik

Index: Rajesha; Mahadevan, Kittappa M.; Satyanarayan; Bhojya Naik Phosphorus, Sulfur and Silicon and the Related Elements, 2011 , vol. 186, # 8 p. 1733 - 1743

Full Text: HTML

Citation Number: 9

Abstract

Abstract A mild and efficient synthesis of new 4-hydroxy-3-(phenylthio)-2 H-chromen-2-ones 4a–k and 4-hydroxy-3-[imidazol/tetrazolo-2-yl) thio]-2 H-chromen-2-ones 6a–d is described. The compounds 4 a–c were further subjected to oxidation by m-CPBA to obtain 3- (phenylsulfonyl)-4-hydroxy-2 H-chromen-2-ones 5a–c. The structures of the resulted new compounds were established by IR, 1H NMR, mass, and elemental analysis. All the ...