Benchmark and Solvent??Free Preparation of Sulfonium Salt Based Electrophilic Trifluoromethylating Reagents

…, C Pradet, JC Blazejewski, E Magnier

Index: Mace, Yohan; Raymondeau, Benoit; Pradet, Charlotte; Blazejewski, Jean-Claude; Magnier, Emmanuel European Journal of Organic Chemistry, 2009 , # 9 p. 1390 - 1397

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Citation Number: 33

Abstract

Abstract Here we describe work devoted to the one-pot preparation of electrophilic trifluoromethylating reagents. The first part describes a reappraisal of our earlier experimental conditions and leads to an improved protocol that avoids the use of solvent and allows better yields. The second part carefully studies the behavior of biaryl substrates, whose structures can drive the reaction through the formation of original noncyclic or ...

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