New catalytic model systems of tyrosinase: fine tuning of the reactivity with pyrazole-based N-donor ligands

JN Hamann, F Tuczek

Index: Hamann, Jessica Nadine; Tuczek, Felix Chemical Communications, 2014 , vol. 50, # 18 p. 2298 - 2300

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Citation Number: 21

Abstract

Two new Cu (I) complexes have been synthesized and investigated as model systems of the enzyme tyrosinase. The corresponding ligands are based on a combination of an imine function with two different pyrazole groups. The reactivity of the prepared systems with respect to the conversion of monophenols to the corresponding ortho-quinones is investigated. The resulting data are compared to results obtained for other catalytic model ...