Development of an Efficient, Scalable Route for the Preparation of a Novel Insulin-Like Growth Factor-1 Receptor Modulator

CHV Kumar, S Kavitake, SS Kumar…

Index: Organic Process Research and Development, , vol. 16, # 8 p. 1416 - 1421

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Abstract

... Organic Process Research & Development. ... This mixture was taken for downstream processing without purification. ... utilizing 6.0 N HCl solution at 20–25 °C. In a further iteration, the isolation of intermediate 19 was avoided, which allowed us to telescope the process from 28 to ...