Studies of hypolipidemic agents. 1. Synthesis and hypolipidemic activities of alkoxycinnamic acid derivatives
T Watanabe, K Hayashi, S Yoshimatsu…
Index: Watanabe; Hayashi; Yoshimatsu; Sakai; Takeyama; Takashima Journal of Medicinal Chemistry, 1980 , vol. 23, # 1 p. 50 - 59
Full Text: HTML
Citation Number: 38
Abstract
More than 110 derivatives of alkoxycinnamic acids were synthesized and their hypolipidemic activities were evaluated in a screening system with rats. Cinnamic acids, a- methylcinnamic acids, and their various esters with a higher p-alkoxy substituent were found to possess hypolipidemic activities higher than or comparable to that of clofibrate. The proper length (C12+ &) and the para position of the alkoxy substituent seem to be ...
Related Articles:
New mesogenic homologous series of Schiff base cinnamates comprising naphthalene moiety
[Prajapati; Thakkar, Viral; Bonde, Nilesh Molecular Crystals and Liquid Crystals, 2003 , vol. 393, p. 41 - 48]
[Chauhan; Doshi Molecular Crystals and Liquid Crystals, 2012 , vol. 569, # 1 p. 33 - 39]
New mesogenic homologous series of Schiff base cinnamates comprising naphthalene moiety
[Prajapati; Thakkar, Viral; Bonde, Nilesh Molecular Crystals and Liquid Crystals, 2003 , vol. 393, p. 41 - 48]