Synthesis of 1-octacosanol and GC-C-IRMS discrimination of samples from different origin

…, A Barge, A Binello, A Albertino, C Aghemo

Index: Cravotto, Giancarlo; Calcio Gaudino, Emanuela; Barge, Alessandro; Binello, Arianna; Albertino, Andrea; Aghemo, Costanza Natural Product Research, 2010 , vol. 24, # 5 p. 428 - 439

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Citation Number: 7

Abstract

Lately, long-chain primary alcohols have been investigated in depth on account of their biological activities. In particular, 1-octacosanol (C28H57OH), the main component of policosanol, the hypolipidaemic fatty alcohol mixture obtained from sugar cane wax, has been the subject of a multitude of pharmacological studies. The aim of this work was to search a convenient synthetic protocol for the preparation of 1-octacosanol in a gram ...

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