A novel synthesis of N-unsubstituted β-enamino thioesters from 3-arylisoxazoles and 3-aryl-5-phenylthio-2-isoxazolines
P Vitale, L Di Nunno, A Scilimati
Index: Vitale, Paola; Di Nunno, Leonardo; Scilimati, Antonio Synthesis, 2010 , # 18 p. 3195 - 3203
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Citation Number: 8
Abstract
Abstract A novel procedure for the synthesis of N-unsubstituted β-enamino thioesters,(Z)-S- phenyl 3-amino-3-arylprop-2-enethioates, from 3-arylisoxazoles or 3-aryl-5-phenylthio-2- isoxazolines is described and a plausible mechanism for the reaction is proposed. Some examples of conversion of one β-enamino thioester [(Z)-S-phenyl 3-amino-3-phenylprop-2- enethioate] into N-unsubstituted β-enaminoacyl derivatives (β-enamino esters, β-enamino ...
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