Nitration of aromatic compounds under neutral conditions using the Ph 2 PCl/I 2/AgNO 3 reagent system
N Nowrouzi, MZ Jonaghani
Index: Nowrouzi, Najmeh; Zareh Jonaghani, Mohammad Tetrahedron Letters, 2011 , vol. 52, # 39 p. 5081 - 5082
Full Text: HTML
Citation Number: 18
Abstract
Aromatic compounds were nitrated efficiently under essentially neutral conditions by employing Ph2PCl in the presence of I2 and AgNO3. This method minimizes waste products compared to traditional methods and gives the corresponding mononitro derivatives in good to excellent yields in dichloromethane at room temperature.
Related Articles:
Regioselective nitration of 3-acetylindole and its N-acyl and N-sulfonyl derivatives
[Ottoni, Olivia; Cruz, Rosimeire; Krammer, Norbert H. Tetrahedron Letters, 1999 , vol. 40, # 6 p. 1117 - 1120]
[Murase; Koike; Moriya; Tobinaga Chemical and Pharmaceutical Bulletin, 1987 , vol. 35, # 7 p. 2656 - 2660]