A Convenient One-Pot Method for the Synthesis of N-Methoxy-N-methyl Amides from Carboxylic Acids
JG Kim, DO Jang
Index: Kim, Joong-Gon; Jang, Doo Ok Bulletin of the Korean Chemical Society, 2010 , vol. 31, # 1 p. 171 - 173
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Citation Number: 7
Abstract
N-Methoxy-N-methyl amides, or Weinreb amides, 1 have been widely used as versatile synthetic intermediates in organic syntheses. 2 These amides serve as excellent acylating agents for organolithium or organomagnesium reagents and as robust aldehyde group equivalents. 3 The utility of Weinreb amides has been extended to the preparation of N- protected amino aldehydes, useful intermediates for many chemoselective ...
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