Journal of Sulfur Chemistry

Efficient synthesis of β, β'-dihydroxy sulfides by ring opening of epoxides with mercaptoethanol catalyzed under solvent-free conditions

M Romdhani-Younes…

Index: Romdhani-Younes, Moufida; Chaabouni, Mohamed Moncef Journal of Sulfur Chemistry, 2012 , vol. 33, # 2 p. 223 - 228

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Citation Number: 2

Abstract

A simple and highly efficient synthesis of β, β'-dihydroxy sulfides has been achieved by ring opening of epoxides with mercaptoethanol using catalytic amount of benzyltrimethylammonium hydroxide (Triton B) under solvent-free conditions. Excellent regioselectivity was found for aliphatic unsymmetrical epoxides, with nucleophilic attack at the less-hindered carbon atom of the epoxide. However, this regioselectivity was not ...