Chemistry Letters

Chemical synthesis of deoxysepiapterin.

R Baur, T Sugimoto, W Pfleiderer

Index: Baur, Ralph; Sugimoto, Takashi; Pfleiderer, Wolfgang Chemistry Letters, 1984 , p. 1025 - 1028

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Citation Number: 10

Abstract

A chemical synthesis of the yellow eye pigment deoxysepiapterin of Drosophila melanogaster has been achieved from 7-alkylthio pteridines by homolytic nucleophilic acylation at C-6 and subsequent hydrolyses to 6-propionylpterin derivatives followed by desulfurizations with copper–aluminum alloy.

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