Total synthesis of myrtucommulone A

H Müller, M Paul, D Hartmann, V Huch…

Index: Mueller, Hans; Paul, Michael; Hartmann, David; Huch, Volker; Blaesius, Dagmar; Koeberle, Andreas; Werz, Oliver; Jauch, Johann Angewandte Chemie - International Edition, 2010 , vol. 49, # 11 p. 2045 - 2049

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Citation Number: 30

Abstract

Myrtucommulone A (1; Figure 1) was first described in 1974 by Kashman and co-workers as a substance found in the common myrtle Myrtus communis L.[1a] These authors also reported that 1 is highly active against Gram-positive bacteria.[1b] Three years later Lounasmaa and co-workers [2] isolated myrtucommuloneA from other members of the myrtacea family. After that, interest in myrtle died down until 2002 when Appendino and co ...