Tetrahedron Letters

Synthesis of 2H-1, 4-benzothiazin-3 (4H)-ones and 2H-1, 4-benzoselenazin-3 (4H)-ones with the aid of samarium (II) iodide

W Zhong, Y Zhang

Index: Zhong, Weihui; Zhang, Yongmin Tetrahedron Letters, 2001 , vol. 42, # 17 p. 3125 - 3127

Full Text: HTML

Citation Number: 13

Abstract

Bis (o-nitrophenyl) disulfides or diselenides were easy to reduce by samarium (II) iodide to produce the active intermediates 2 in situ, which readily react with α-halocarboxylic derivatives to yield the corresponding products 2H-1, 4-benzothiazin-3 (4H)-ones and 2H-1, 4-benzoselenazin-3 (4H)-ones, respectively, in moderate to high yields under mild conditions.

Related Articles:

Regioselective one pot synthesis of 2??alkyl/aryl??4h??benzo [1, 4] thiazine??3??one via microwave irradiation

[Kamila, Sukanta; Koh, Benjamin; Khan, Omair; Zhang, Hongming; Biehl, Edward R. Journal of Heterocyclic Chemistry, 2006 , vol. 43, # 6 p. 1641 - 1646]

On the reaction of chloroalkylbenzothiazoles with alkoxides

[Florio, Saverio; Capriati, Vito; Colli, Gennara Tetrahedron, 1997 , vol. 53, # 16 p. 5839 - 5846]

Studies on antidiabetic agents. IX. A new aldose reductase inhibitor, AD-5467, and related 1, 4-benzoxazine and 1, 4-benzothiazine derivatives: Synthesis and …

[Tawada; Sugiyama; Ikeda; Yamamoto; Meguro Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 5 p. 1238 - 1245]

Eliminative ring fission of 4-acyl-2, 3-dihydro-4H-1, 4-benzothiazines

[Babudri, F.; Florio, S.; Indelicati, G.; Trapani, G. Journal of Organic Chemistry, 1983 , vol. 48, # 22 p. 4082 - 4087]

On the reaction of chloroalkylbenzothiazoles with alkoxides

[Florio, Saverio; Capriati, Vito; Colli, Gennara Tetrahedron, 1997 , vol. 53, # 16 p. 5839 - 5846]

More Articles...