Chemoenzymatic synthesis of both enantiomers of cispentacin
F Theil, S Ballschuh
Index: Theil, Fritz; Ballschuh, Sibylle Tetrahedron Asymmetry, 1996 , vol. 7, # 12 p. 3565 - 3572
Full Text: HTML
Citation Number: 42
Abstract
Based on the lipase-catalysed kinetic resolution of the silyloxyalcohol (1RS, 2SR)-5 by transesterification with vinyl acetate in the presence of lipase from Pseudomonas cepacia a synthesis of both enantiomers of the β-amino acid cispentacin (1R, 2S)-1 and (1S, 2R)-1 using simple functional group interconversions is described.
Related Articles:
[Aggarwal, Varinder K; Roseblade, Stephen; Alexander, Rikki Organic and biomolecular chemistry, 2003 , vol. 1, # 4 p. 684 - 691]
[Organic letters, , vol. 5, # 8 p. 1209 - 1212]
[Organic and biomolecular chemistry, , vol. 1, # 4 p. 684 - 691]
[Organic and biomolecular chemistry, , vol. 1, # 4 p. 684 - 691]
[Organic and biomolecular chemistry, , vol. 1, # 4 p. 684 - 691]