Antimalarials. III. Benzothiazole amino alcohols
A Burger, SN Sawhney
Index: Burger,A.; Sawhney,S.N. Journal of Medicinal Chemistry, 1968 , vol. 11, # 2 p. 270 - 273
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Citation Number: 59
Abstract
Ib, n= 3 mouse by the procedure of Rane, et aZ. 13 Deaths occurring on days 2-5 after infection were attributed to drug action; infected control animals did not die before day 6. These compounds were highly toxic at 160-640 mg/kg. They exhibited negligible antimalarial action at lower doses, were not curative at 40-640 mg/kg, and increased survival time from 0.3-2.9 days only. Substitution by phenyl or trifluoromethyl at position 2 ...
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