The Journal of organic chemistry

Click chemistry to construct fluorescent oligonucleotides for DNA sequencing

TS Seo, Z Li, H Ruparel, J Ju

Index: Journal of Organic Chemistry, , vol. 68, # 2 p. 609 - 612

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Citation Number: 275

Abstract

... The Journal of Organic Chemistry. ... gel TLC plate (1:9 MeOH/CHCl 3 ) to give 8.0 mg (85%) of alkynyl FAM (R f = 0.45) as a red oil: 1 H NMR (methanol-d 4 ) δ 8.01 (s, 2H), 7.60 (s, 1H), 6.94 (d, 2H, J = 9.1 Hz), 6.58−6.53 (m, 4H), 4.05 (d, 2H, J = 2.4 Hz), 2.50 (t, 1H, J = 2.2 Hz ...

Facile and chemoselective reduction of carboxylic acids to alcohols using BOP reagent and sodium borohydride

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Altering peptide fibrillization by polymer conjugation

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Synthesis of C α methylated carboxylic acids: isosteres of arginine and lysine for use as N-terminal capping residues in polypeptides

[Tetrahedron Letters, , vol. 46, # 41 p. 7007 - 7009]