Efficient Synthesis of Cyclopropane??Fused Heterocycles with Bromoethylsulfonium Salt
SP Fritz, JV Matlock, EM McGarrigle…
Index: Fritz, Sven P.; Matlock, Johnathan V.; McGarrigle, Eoghan M.; Aggarwal, Varinder K. Chemistry - A European Journal, 2013 , vol. 19, # 33 p. 10827 - 10831
Full Text: HTML
Citation Number: 14
Abstract
The 3-azabicycloACHTUNGTRENNUNG [3.1. 0] hexane is a common motif in natural products.[1–6] Furthermore this rigid framework represents a privileged class of pharmacologically active compounds, often showing enhanced binding affinities with their targets (Figure 1).[7] These bicycles also represent conformationally restricted analogues of piperidines (eg trovafloxacin).[8] When substituted with a carboxylic acid moiety, they ...
Related Articles:
[Anquetin; Rouquayrol; Mahmoudi; Santillana-Hayat; Gozalbes; Greiner; Farhati; Derouin; Guedj; Vierling Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 11 p. 2773 - 2776]
[Anquetin; Rouquayrol; Mahmoudi; Santillana-Hayat; Gozalbes; Greiner; Farhati; Derouin; Guedj; Vierling Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 11 p. 2773 - 2776]
[Anquetin; Rouquayrol; Mahmoudi; Santillana-Hayat; Gozalbes; Greiner; Farhati; Derouin; Guedj; Vierling Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 11 p. 2773 - 2776]
[Anquetin; Rouquayrol; Mahmoudi; Santillana-Hayat; Gozalbes; Greiner; Farhati; Derouin; Guedj; Vierling Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 11 p. 2773 - 2776]