Stille cross-couplings of unactivated secondary alkyl halides using monoorganotin reagents

DA Powell, T Maki, GC Fu

Index: Powell, David A.; Maki, Toshihide; Fu, Gregory C. Journal of the American Chemical Society, 2005 , vol. 127, # 2 p. 510 - 511

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Citation Number: 129

Abstract

The first catalyst that achieves Stille cross-couplings of secondary (as well as primary) alkyl halides has been developed. The method employs easily handled and inexpensive catalyst components (NiCl2 and 2, 2'-bipyridine) and, through the use of monoorganotin reagents, avoids the formation of toxic and difficult-to-remove triorganotin side products.

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