Synthesis of (2S, 3R)-3-amino-2-hydroxy-5-methylhexanoic acid derivatives. Application to the synthesis of amastatin, an inhibitor of aminopeptidases

DH Rich, BJ Moon, AS Boparai

Index: Journal of Organic Chemistry, , vol. 45, # 12 p. 2288 - 2290

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Citation Number: 47

Abstract

... added, and the reaction mixture was stirred at room temperature for 4 h. The organic phase was ... 8 Hz, 1 H), 6.76 (d, J = 10 Hz, 1 H), 6.99 (d, J = 10 Hz, 1 ... Department of Chemistry, Simon Fraser University, Burnaby, British Columbia, Canada V5A IS6 Received November 5, 1979 ...