Discovery of 8-cyclopentyl-2-[4-(4-methyl-piperazin-1-yl)-phenylamino]-7-oxo-7, 8-dihydro-pyrido [2, 3-d] pyrimidine-6-carbonitrile (7x) as a potent inhibitor of cyclin- …

MVR Reddy, B Akula, SC Cosenza…

Index: Journal of Medicinal Chemistry, , vol. 57, # 3 p. 578 - 599

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Citation Number: 19

Abstract

... Journal of Medicinal Chemistry. ... Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, New York, New York 10029-6514, United States. ‡ Department of Medicinal Chemistry, Onconova Therapeutics Inc., 375 Pheasant ...