Diethyldithiocarbamic acid S-oxide: a new class of sulfine

Y Watanabe, Y Ishimura

Index: Watanabe, Yoshihito; Ishimura, Yuzuru Journal of Organic Chemistry, 1988 , vol. 53, # 9 p. 2119 - 2120

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Citation Number: 12

Abstract

Sodium diethyldithiocarabamate (la) has been widely used as a copper trapping reagent. Thus, the inhibition of an enzymatic reaction by la has been regarded as a proof of the participation of copper in the reaction.'However, we previously noted that the inhibitory effect of la on the oxygenase activity of L-tryptophan 2, 3-di-oxygenase was caused by its rapid reaction with hydrogen peroxide, the activator of the enzyme, instead of the chelation with ...