Journal of Chemical Research

InCl3· 4H2O/TMSCl-catalysed aldol reaction of aromatic aldehydes with cycloalkanones in ionic liquid medium

X Hu, X Fan, X Zhang, J Wang

Index: Hu, Xueyuan; Fan, Xuesen; Zhang, Xinying; Wang, Jianji Journal of Chemical Research, 2004 , # 10 p. 684 - 686

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Citation Number: 15

Abstract

The aldol-type reaction is one of the most powerful tools for the construction of carbon–carbon bonds.1 Of which, the condensation of cycloalkanones with aldehydes to give the corresponding α,α'-bis(substituted benzylidene) cycloalkanones has been of special interest recently due to the increasing importance of α,α'-bis(substituted benzylidene) cyclo- alkanones as useful precursors to potentially bioactive pyrimidine derivatives.2 Classically, the synthesis of this kind of ...