Synthesis of Potential Anticancer Agents. XII. 9-Alkyl-6-substituted-purines2
JA Montgomery, C Temple Jr
Index: Montgomery; Temple Journal of the American Chemical Society, 1958 , vol. 80, p. 409
Full Text: HTML
Citation Number: 32
Abstract
The 9-n-butyl, 9-cyclopentyl and 9-cyclohexyl analogs of purine, adenine and 6- mercaptopurine have been prepared from the corresponding 9-alkyl-6-chloropurines. The chloropurines and the hypoxanthine analogs were prepared by the reaction of the appropriate 4-alkylamino-5-amino-6-chloropyrimidines with diethoxymethyl acetate and formic acid, respectively.
Related Articles:
[Ghosh, Kumaresh; Sen, Tanushree Beilstein Journal of Organic Chemistry, 2010 , vol. 6, art. no. 44]
[Zhang, Lin; Fan, Junhua; Vu, Khang; Hong, Kevin; Le Brazidec, Jean-Yves; Shi, Jiandong; Biamonte, Marco; Busch, David J.; Lough, Rachel E.; Grecko, Roy; Ran, Yingqing; Sensintaffar, John L.; Kamal, Adeela; Lundgren, Karen; Burrows, Francis J.; Mansfield, Robert; Timony, Gregg A.; Ulm, Edgar H.; Kasibhatla, Srinivas R.; Boehm, Marcus F. Journal of Medicinal Chemistry, 2006 , vol. 49, # 17 p. 5352 - 5362]
Synthesis and crystal structures of fluorescent receptors for 9-butyladenine
[Lamale, Bassam; Henry, William P.; Daniels, Lee M.; Zhang, Cungen; Klein, Suzane M.; Jiang, Yu Lin Tetrahedron, 2009 , vol. 65, # 1 p. 62 - 69]