Synthesis and binding affinity of a fluorine-substituted peroxisome proliferator-activated gamma (PPARγ) ligand as a potential positron emission tomography (PET) …

BC Lee, KC Lee, H Lee, RH Mach…

Index: Gabbutt, Christopher D.; Heron, B. Mark; Instone, Alicia C. Heterocycles, 2003 , vol. 60, # 4 p. 843 - 855

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Abstract

... q, J = 8.0 Hz, 1H), 4.23 (t, J = 6.4 Hz, 2H), 6.92 (d, J = 8.4 Hz, 2H), 7.18 (d, J = 8.4 ... After the mixture was stirred at 100 °C for 4 h, the cooled solution was concentrated in vacuo. ... Method B. To a solution of trifluoroacetate salt 16 (5.0 mg, 10.4 μmol) in acetonitrile (1 mL) was added ...

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