Tetrahedron

Studies on organophosphorus compounds—VI: Dimethylamino-heterocyclic compounds from the corresponding potential hydroxy-compounds and HMPA

EB Pedersen, SO Lawesson

Index: Pedersen,E.B.; Lawesson,S.-O. Tetrahedron, 1974 , vol. 30, p. 875 - 878

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Citation Number: 24

Abstract

Potential hydroxy heterocyclic compounds are heated in HMPA at 220–230° for 20 min-15 h. The OH Group is thereby replaced by a dimethylamino-group and the yields for the reactions are indicated for the following compounds: 2-Dimethylamino-quinoline (79%); 2- dimethylamino-lepidine (77%); 2-dimethylamino-benzo [b] furan (47%); 2-dimethylamino-1- methyl-indole (68%); 2-di-methylamino-thiophene (3%); 2-dimethylamino-5-methyl- ...