Improved etherification procedure for the preparation of dibenz [b, f][1, 4] oxazepine

…, A Yarahmadi, H Hadj??Ghanbary

Index: Fakhraian; Nafary; Yarahmadi; Hadj-Ghanbary Journal of Heterocyclic Chemistry, 2008 , vol. 45, # 5 p. 1469 - 1471

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Citation Number: 4

Abstract

Dibenz [b, f][1, 4] oxazepine (4) is an incapacitating and a lachrymatory agent [1-6]. It is chemically related to loxapine (antipsychotic), amoxapine (antidepressant)[7] and others substituted dibenzoxazepine compounds that are analgesic or useful for the treatment of various diseases [8-10]. There are different methods for the preparation of this compound [11-19]. Tambute et al. described the use of 1-chloro-2-nitrobenzene and salicylaldehyde ...

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