Tetrahedron letters

Novel synthon for incorporating 1, 3-dimethyl-imidazolium group into molecular architecture

M Berezin, S Achilefu

Index: Berezin, Mikhail; Achilefu, Samuel Tetrahedron Letters, 2007 , vol. 48, # 7 p. 1195 - 1199

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Citation Number: 8

Abstract

The synthesized 1, 3-dimethylated imidazolium-carbaldehydes serves as synthons for incorporating a permanently cationic imidazolium group into molecular framework. The utility of new synthon was demonstrated in a variety of reactions: Knoevenagel, Wittig, Schiff base formation, based-mediated electrophilic substitution, and oxidation, including synthesis of the natural product norzooanemonin.

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