Preparation and reactivity of highly functionalized organometallics at the. alpha. position of oxygen or nitrogen

P Knochel, TS Chou, C Jubert…

Index: Knochel, Paul; Chou, Tso-Sheng; Jubert, Carole; Rajagopal, Duddu Journal of Organic Chemistry, 1993 , vol. 58, # 3 p. 588 - 599

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Citation Number: 79

Abstract

Functionalized organometallics are important intermediates in organic synthesis. The preparation and the reaction of lithium carbanions at the a-position to oxygen or nitrogen has been an active area of research leading to numerous synthetic application^.^^^ However, the high reactivity of the carbon-lithium bond has prevented the presence of most organic functionalities in these molecules and has limited the synthetic scope of these ...