Oxidation of 2, 6-dimethylaniline by recombinant human cytochrome P450s and human liver microsomes

J Gan, PL Skipper, SR Tannenbaum

Index: Sorkin; Hinden Helvetica Chimica Acta, 1949 , vol. 32, p. 63,66

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Citation Number: 29

Abstract

... Microsomal incubations were conducted at 37 °C in 100 mM phosphate buffer (pH 7.4; total volume 0.2 mL) containing an NADPH regeneration system ... The effects of KTZ, coumarin, 4-MP, and orphenadrine on the p-hydroxylation of 2,6-DMA in liver microsomes are shown in ...