Synthesis, complete NMR spectral assignments, and antifungal screening of new 2, 4-diaryl-3-azabicyclo [3.3. 1] nonan-9-one oxime derivatives

P Parthiban, P Rathika, KS Park, YT Jeong

Index: Parthiban, Paramasivam; Rathika, Paramasivam; Park, Keun Soo; Jeong, Yeon Tae Monatshefte fur Chemie, 2010 , vol. 141, # 1 p. 79 - 93

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Citation Number: 17

Abstract

Abstract A series of differently substituted 2, 4-diaryl-3-azabicyclo [3.3. 1] nonan-9-one oximes have been synthesized and their 1 H and 13 C NMR chemical shifts have been unambiguously assigned using H, H-COSY, NOESY, HSQC, and HMBC spectral data. On the basis of the NMR studies, irrespective of the nature and position of the substituents, all reported compounds exist in twin-chair conformation with equatorial disposition of the ...