Substituted Imidazoles as Precursors of the Purines1

CS Miller, S Gurin, DW Wilson

Index: Miller, Charles S.; Gurin, Samuel; Wilson, D. Wright Journal of the American Chemical Society, 1952 , vol. 74, # 11 p. 2892 - 2894

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Abstract

In an earlier report from this Laboratory, S a new and convenient synthesis of C14-labeled 4 (5)-amino-5 (4)-imidazolecarboxamide was described. It was also demonstrated that this substance is utilized by the rat not only for the biosynthesis of adenine and guanine derived from nucleic acids, but also for nucleotide adenine and urinary allantoin.