Proline-catalyzed synthesis of 5-aryl-2-oxazolidinones from carbon dioxide and aziridines under solvent-free conditions

XY Dou, LN He, ZZ Yang

Index: Dou, Xiao-Yong; He, Liang-Nian; Yang, Zhen-Zhen Synthetic Communications, 2012 , vol. 42, # 1 p. 62 - 74

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Citation Number: 14

Abstract

Natural α-amino acids were proven to be ecofriendly and recyclable catalysts for the carboxylation of aziridines with CO 2 without utilization of any organic solvents or additives. Notably, a series of 5-aryl-2-oxazolidinones were obtained in good yield together with excellent chemo- and regioselectivity under mild conditions using proline as the catalyst. Notably, the catalyst could be recycled more than five times after a simple separation procedure without appreciable loss of catalytic ...