Highly Efficient Brønsted Acid??Catalyzed Cycloisomerizations of Alkynes Bearing Bis (acetoxy) Groups to Indenyl Ketones

…, G Li, B Yan, S Guo, Y Zhou, H Zhang…

Index: Liu, Yuanhong; Zhou, Shaolin; Li, Guijie; Yan, Bin; Guo, Shenghai; Zhou, Yebing; Zhang, Hao; Wang, Peng George Advanced Synthesis and Catalysis, 2008 , vol. 350, # 6 p. 797 - 801

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Citation Number: 17

Abstract

Abstract A Brønsted acid-catalyzed cycloisomerization of functionalized alkynes is described, which is assumed to be initiated through the formation of a benzylic cation intermediate. The reaction offers a highly efficient and straightforward route to indenyl ketones with a wide range of substituents under mild conditions.